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Labyrint: Geestverruimende Therapie

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Paddo’s gebruiken om depressieve klachten te bestrijden? Of LSD-therapie om van je rookverslaving af te komen? Op 19 december 2012 zond Labyrint TV een aflevering uit over grensverleggend onderzoek naar het gebruik van psychedelica in de behandelkamer van de psychiater. Gefilmd tijdens Stichting OPEN’s Interdisciplinary Conference on Psychedelic Research in 2012.

Voor het eerst uitgezonden op 19 december 2012.[/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]

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Labyrint: Mindblowing Therapy?

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Will we be using Magic Mushrooms to fight depression? Or get an LSD treatment to cure your smoking addiction? On December 19 2012 Dutch Labyrint TV screened an episode about groundbreaking research using psychedelics in psychiatric treatment. Interviews with the scientists were filmed at OPEN’s Interdisciplinary Conference on Psychedelic Research in 2012.

First broadcast on the 19th of December, 2012 (English subtitles)

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Labyrint TV special over therapieën met psychedelica

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Komende week op Wetenschap24 rapporteert Labyrint TV over grensverleggend onderzoek naar het gebruik van psychedelica in de behandelkamer van de psychiater.

De aflevering is gefilmd op het door OPEN georganiseerde Interdisciplinary Conference on Psychedelic Research 2012 en neemt je mee vanaf het eerste wetenschappelijk onderzoek naar psychedelica in de jaren ’50, het recreatieve gebruik en het verbod op deze middelen, naar het recente onderzoek naar psychedelica als potentiële hulpmiddelen bij psychotherapie. Onder andere de Britse psychofarmacoloog Robin Carhart-Harris en psychofarmacoloog Matthew Johnson, beiden sprekers op ICPR 2012, zullen in de uitzending zijn te zien, waar ze uitgebreid zullen vertellen over hun onderzoek en de potentiële toepassingen van psilocybine.

Vergeet dus vooral niet te kijken aankomende woensdag 19 december, om 20u50 op Nederland 2.

Meer informatie vind je op de Labyrint TV website.

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Labyrint TV special about therapy with psychedelics

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psionderzoek

Next week on Wetenschap24 Labyrint TV reports on groundbreaking research into the use of psychedelics for the treatment of psychological disorders.

The episode was filmed at the Interdisciplinary Conference on Psychedelic Research 2012 and takes you from the first scientific research into psychedelics in the ’50s, the recreational use and the prohibition of these substances, to the recent research into psychedelics as potential tools for psychotherapy. Amongst others, the British psychopharmacologists Robin Carhart–Harris and Matthew Johnson, both speakers at ICPR 2012, will appear in this episode. They will speak about their research into the therapeutic potential of psilocybin.

Next Wednesday, December 19th, 8:50pm at Nederland 2.

More information on the Labyrint TV website.

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Universiteitsblad Folia en psychedelisch onderzoek

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Universiteitsblad Folia staat dit nummer in het teken van onderzoek naar psychedelica. De cover is helemaal gewijd aan het artikel ‘Trippen op recept’. Bezoekers van het Interdisciplinary Conference on Psychedelic Research zullen de experts die aan het woord komen zeker herkennen. Zo vertelt Ben Sessa over zijn ervaring in een fMRI scanner tijdens een onderzoek naar de effecten van psilocybine in het brein. Robert Carhart-Harris, onderzoeker aan Imperial College Londen, vertelt over de eerste bevindingen van dit onderzoek. Ook Matthew Johnson, psychofarmacoloog aan de Johns Hopkins University School of Medicine in de Verenigde Staten komt aan het woord. Hij vertelt over zijn onderzoek naar het gebruik van psilocybine bij tabaksverslaafden.

Je kunt de Folia vinden op allerlei locaties van de Universiteit van Amsterdam en de Hogeschool van Amsterdam. Maar je kan het ook digitaal op de Folia website vinden.

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Article in university magazine Folia about psychedelic research

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University magazine Folia devoted an article to psychedelic research. The cover is entirely dedicated to the article ‘Trippen op recept’ (Tripping on prescription). Visitors of the Interdisciplinary Conference on Psychedelic Research will recognize the interviewed experts. Ben Sessa talks about his experience in an fMRI scanner when he participated in a study into the effects of psilocybin on the brain. Robin Carhart-Harris, a researchers at Imperial College London, talks about initial findings of this study. Matthew Johnson, psychopharmacologist at Johns Hopkins University School of Medicine (United States) is interviewed as well. He talks about his research into the use of psilocybin in the treatment of tobacco addiction.

You can find the Folia magazine at various locations at the University of Amsterdam. You can also find it digitally on the Folia website.

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Durability of improvement in posttraumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study

/ Anxiety Disorders / PTSD, MDMA, Papers, Psychology, Publications / / , , , , , ,

Abstract

We report follow-up data evaluating the long-term outcomes for the first completed trial of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment-resistant post-traumatic stress disorder (PTSD) (Mithoefer et al., 2011). All of the 19 subjects who received MDMA-assisted treatment in the original trial participated in the long-term follow-up (LTFU), with 16 out of 19 completing all of the long-term outcome measures, which were administered from 17 to 74 months after the original study’s final MDMA session (mean = 45.4; SD = 17.3). Our primary outcome measure used was the Clinician-Administered PTSD Scale (CAPS). Secondary outcome measures were the Impact of Events Scale-Revised (IES-R) and the Neuroticism Extroversion Oppenness Personality Inventory-Revised (NEO PI-R) Personality Inventory. We also collected a long-term follow-up questionnaire. Results for the 16 CAPS completers showed there were no statistical differences between mean CAPS score at LTFU (mean = 23.7; SD = 22.8) (t_matched = 0.1; df = 15, p = 0.91) and the mean CAPS score previously obtained at Study Exit (mean = 24.6, SD = 18.6). On average, subjects maintained statistically and clinically-significant gains in symptom relief, although two of these subjects did relapse. It was promising that we found the majority of these subjects with previously severe PTSD who were unresponsive to existing treatments had symptomatic relief provided by MDMA-assisted psychotherapy that persisted over time, with no subjects reporting harm from participation in the study.

Mithoefer, M.C., Wagner, M. T., Mithoefer, A. T., Jerome, L., Martin, S. F., Yazar-Klosinski, B., … Doblin, R. (2012). Durability of improvement in posttraumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study. Journal of Psychopharmacology, 27(1), 1-12. http://dx.doi.org/10.1177/0269881112456611
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A randomized, controlled pilot study of MDMA (± 3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD)

/ Anxiety Disorders / PTSD, MDMA, Papers, Psychology, Publications / / , , ,

Abstract

Psychiatrists and psychotherapists in the US (1970s to 1985) and Switzerland (1988-1993) used MDMA legally as a prescription drug, to enhance the effectiveness of psychotherapy. Early reports suggest that it is useful in treating trauma-related disorders. Recently, the first completed pilot study of MDMA-assisted psychotherapy for PTSD yielded encouraging results. Designed to test the safety and efficacy of MDMA-assisted psychotherapy in patients with treatment-resistant PTSD; our randomized, double-blind, active-placebo controlled trial enrolled 12 patients for treatment with either low-dose (25 mg, plus 12.5 mg supplemental dose) or full-dose MDMA (125 mg, plus 62.5 mg supplemental dose). MDMA was administered during three experimental sessions, interspersed with weekly non-drug-based psychotherapy sessions. Outcome measures used were the Clinician-Administered PTSD Scale (CAPS) and the Posttraumatic Diagnostic Scale (PDS). Patients were assessed at baseline, three weeks after the second and third MDMA session (end of treatment), and at the 2-month and 1-year follow-ups. We found that MDMA-assisted psychotherapy can be safely administered in a clinical setting. No drug-related serious adverse events occurred. We did not see statistically significant reductions in CAPS scores (p = 0.066), although there was clinically and statistically significant self-reported (PDS) improvement (p = 0.014). CAPS scores improved further at the 1-year follow-up. In addition, three MDMA sessions were more effective than two (p = 0.016).

Oehen, P., Traber, R., Widmer, V., & Schnyder, U. (2012) A randomized, controlled pilot study of MDMA (± 3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD). Journal of Psychopharmacology, 27(1), 40-52. http://dx.doi.org/10.1177/0269881112464827
Link to full text

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Veel aandacht voor uitverkocht ICPR 2012

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Op 6 en 7 oktober vond OPEN’s tweede grote internationale congres plaats in Amsterdam: de Interdisciplinary Conference on Psychedelic Research. In de uitverkochte Mozes en Aäronkerk kwamen meer dan 400 onderzoekers, studenten, therapeuten en wetenschappers bijeen om te luisteren naar lezingen, variërend van fMRI-onderzoek naar psilocybine, filosofische discussies over de rol van psychedelische ervaringen tot een debat over de plaats en het nut van MDMA in psychotherapie.

Onderzoek naar psychedelica wordt langzaam ook in Nederland serieus genomen. VPRO’s Labyrint heeft opnames gemaakt voor een uitzending gewijd aan psychedelisch onderzoek. Lees ook de artikelen in het wetenschapskatern van de Volkskrant (6 okt. ’12) en het Parool (13 okt. ’12). Foto’s van het congres kunnen hier worden gevonden en video’s worden momenteel gemonteerd en zullen spoedig op de website verschijnen.

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ICPR 2012 draws attention to psychedelic research

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On October 6 & 7 OPEN’s second international conference took place in Amsterdam: the Interdisciplinary Conference on Psychedelic Research. In a sold out Mozeskerk over 400 researchers, students, therapists and scholars gathered to listen and discuss the latest psychedelic research. From brain imaging studies on psilocybin, philosophical discussions on the meaning of altered states of consciousness to a debate on the place of MDMA in psychotherapy, ICPR set the standard for future events.

Research into psychedelics is slowly being taken seriously in the Netherlands. Dutch science program Labyrint recorded interviews and shot the conference for an episode on psychedelic research. Articles on the conference in Dutch national newspapers Volkskrant (6 Oct. ’12) and Parool (13 Oct. ’12) can be clicked and read here (only in Dutch). Photos of the conference can be found here and videos of the conference are being edited and will be put on our website soon.

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Breath and Body: Scientific and Experiential Perspectives on Breathwork - September 23rd

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