OPEN Foundation

N. Strauss

Psilocybin-assisted therapy for depression: How do we advance the field?

Abstract

In the quest for new treatment options for depression, attention is being paid to the potential role of psychedelic drugs. Psilocybin is of particular interest given its mechanism of action, its benefits in early trials and its relatively low side effects burden. This viewpoint outlines a number of key issues that remain to be elucidated about its potential use in the clinical environment, including clarification of the profile of people most likely to benefit and those who might experience adverse effects, longer-term outcomes and the role of psychotherapeutic input alongside the drug itself. There are also opportunities to understand better, the neurobiology underpinning its effects.

Meikle, S. E., Liknaitzky, P., Rossell, S. L., Ross, M., Strauss, N., Thomas, N., … & Castle, D. J. (2019). Psilocybin-assisted therapy for depression: How do we advance the field?. Australian & New Zealand Journal of Psychiatry, 0004867419888575., https://doi.org/10.1177/0004867419888575
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Psilocybin-assisted therapy for anxiety and depression: implications for euthanasia

Abstract

Despite their stigmatisation, psychedelic drugs are once again being clinically researched in Europe and North America. This long-awaited renaissance is showing very promising results and, unlike the pioneering research that occurred before these drugs were outlawed over 30 years ago, the current methodology is rigorous and of a very high standard.
Strauss, N. (2017). Psilocybin-assisted therapy for anxiety and depression: implications for euthanasia. The Medical Journal of Australia206(11), 468-469. 10.5694/mja17.00081
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Australia should be initiating a psychedelic research program: What are the barriers?

Strauss, N., Bright, S. J., & Williams, M. L. (2016). Australia should be initiating a psychedelic research program: What are the barriers?. Australian and New Zealand Journal of Psychiatry, 50(11), 1036-1037. 10.1177/0004867416670520
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