OPEN Foundation

Microdosing Results, Limitations, & Emerging Questions: A Conversation with Jim Fadiman

🗣 James Fadiman, PhD (Psychologist & Researcher)

⏰ Tuesday 9 September, 2025 8PM CEST (7PM BST, 2PM ET, 11AM PT)

📍 Online via Zoom

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Microdosing psychedelics has captured global attention in recent years, driven by powerful personal stories of enhanced mood, focus, and well-being. But what do we truly know about its effectiveness and safety?
In this session, we sit down with Dr. Jim Fadiman, early psychedelic researcher and co-author of Microdosing for Health, Healing, and Enhanced Performance, to explore the current state of knowledge, ongoing controversies, and the broader implications of this emerging practice.
 
Dr. Fadiman is known for his citizen science approaches to microdosing, collecting thousands of self-reports from individuals around the world. These accounts describe a wide range of improvements, from alleviating depression, chronic pain, and ADHD symptoms to supporting palliative care, creativity, and tapering off antidepressants. At the same time, any intervention claiming to affect so many conditions should invite rigorous scrutiny and appropriate research designs.
 
This conversation will explore the differences between self-reported outcomes and clinical trials, the confusion between high-dose and microdosing research results, and future directions to determine efficacy in different populations.

Unpack the Evidence

By joining this conversation, you’ll gain clarity on what microdosing can and can’t offer, grounded in both real-world accounts and rigorous science. You’ll walk away with:
  • An understanding of citizen science and real-world evidence contributes to our current understanding of microdosing and better-focused clinical research and appropriate methodology.
  • Insight into key areas of reported benefit, including mood, focus, and mental health, a growing number of physical conditions, alongside known risks and contraindications.
  • Knowledge of ongoing challenges in research methodology, including the limitations of clinical trials and double-blind studies, and the need to develop more useful measuring tools better suited to analysing long-term psychedelic effects.
Designed for Enthusiasts and Practitioners Like You
If you want to engage with the current science and controversies around microdosing, this event is for you. You’ll get the most out of it if you:
  • Are a researcher or clinician seeking actionable insights and fresh frameworks for your work.
  • Work as a therapist or facilitator supporting clients who use or ask about microdosing.
  • Have personal experience with microdosing and want to make sense of your own or others’ reports.
  • Are a student, educator, or advocate seeking a deeper understanding of current debates.
Save your spot today and join a thoughtful, evidence-informed discussion with Dr. Jim Fadiman. Gain insights you can bring into your work, practice, or personal journey, and be part of shaping the conversation around microdosing.

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ABOUT THE SPEAKERs

James Fadiman (BA from Harvard and an MA and PhD from Stanford) was introduced to psychedelics by his undergraduate mentor, Richard Alpert (Ram Dass), and began to research psychedelics in the 1960s. He has run his own management consulting firm, helped found a still-functioning commune in New Mexico, managed 20,000 acres of timberland in Mississippi, and taught Psychology at San Francisco State, Sonoma State, and Brandeis universities. He worked in the Counseling Center and taught in Design Engineering at Stanford and co-authored a textbook, Personality and Personal Growth (7 editions and translations). He has written professional books, a self-help book, The Other Side of Haight, a psychedelic novel, and The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys. He also had a play produced, held several solo photography exhibitions, and is a founder of Transpersonal Psychology and co-founder of The Institute for Transpersonal Psychology (now Sofia University). Recent books (both with Jordan Grube) are Your Symphony of Selves: Discover and Understand More of Who We Are, an observational study of healthy inner multiplicity, and Microdosing for Health, Healing, and Enhanced Performance.

He has been called “the father of modern microdosing” for his early creation and research into the first effective clinical and wellness microdosing protocols. He has consulted and advised myriad psychedelic companies and appeared on a number of podcasts. He is married to a gifted social activist filmmaker.

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Microdosing Results, Limitations, & Emerging Questions: A Conversation with James Fadiman - September 9th