Ketamine, an NMDA (N-methyl-d-aspartate) glutamate antagonist, commonly used as an anesthetic agent, has emerged as a major substance of abuse particularly in Asia.1 Here, we present, to our knowledge, the first case of a patient who developed major depressive episodes after heavy and long-term ketamine use.
Chang, H., Huang, M. C., & Chen, L. Y. (2016). Major Depressive Disorder Induced by Chronic Ketamine Abuse: A Case Report. The Primary Care Companion for CNS Disorders, 18(3). 10.4088%2FPCC.15l01881
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