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Depression: Ketamine steps out of the darkness

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Abstract

The way in which ketamine exerts its antidepressant effects has been perplexing. Evidence that a metabolite of the drug is responsible, and acts on a different target from ketamine, might be the key to an answer.

Malinow, R. (2016). Depression: Ketamine steps out of the darkness. Nature. http://dx.doi.org/10.1038/nature17897

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