OPEN Foundation

Spirituality

Forbidden therapies: Santo Daime, ayahuasca, and the prohibition of entheogens in Western society

Abstract

Santo Daime, a Brazilian religion organized around a potent psychoactive beverage called ayahuasca, is now being practiced across Europe and North America. Deeming ayahuasca a dangerous “hallucinogen,” most Western governments prosecute people who participate in Santo Daime. On the contrary, members of Santo Daime (called “daimistas”) consider ayahuasca a medicinal sacrament (or “entheogen”). Empirical studies corroborate daimistas’ claim that entheogens are benign and can be beneficial when employed in controlled contexts. Following from anthropology’s goal of rendering different cultural logics as mutually explicable, this article intercedes in a misunderstanding between policies of prohibition and an emergent subculture of entheogenic therapy.

Blainey, M. G. (2015). Forbidden therapies: Santo Daime, ayahuasca, and the prohibition of entheogens in western society. Journal of religion and health, 54(1), 287-302. 10.1007/s10943-014-9826-2
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Editorial (Thematic Issue: Introduction to 'Beneficial Effects of Psychedelics with a Special Focus on Addictions')

Editorial

Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’

We are witnessing a revival of psychedelic research. An increasing number of studies investigating the therapeutic use of psychedelics are currently underway at some of the most renowned universities. Dedicating a second issue of ‘Current Drug Abuse Reviews’ to psychedelics aims to keep up with this blossoming field. With the availability of modern scientific instruments, psychedelic research is once again gaining a firm foothold in academia.

The idea of this special issue originated at the Interdisciplinary Conference on Psychedelic Research, organised by the OPEN Foundation in 2012. OPEN was founded in 2007 in the Netherlands, in order to stimulate and advance scientific research into psychedelics. This special issue of CDAR takes an interdisciplinary approach to the topic of psychedelics and mental health, while maintaining a particular focus on applications of psychedelics in the fields of substance abuse and addiction. This special issue also takes a critical look at some widespread assumptions about psychedelics, introduces new ideas and suggests novel directions for future research.

Kortekaas, R., & Breeksema, J. J. (2015). Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’. Current Drug Abuse Reviews, 7(2), 69-70. https://dx.doi.org/10.2174/1874473708666150120114604

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Articles in this special issue:

Editorial (Thematic Issue: Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’)
Ayahuasca, Psychedelic Studies and Health Sciences: The Politics of Knowledge and Inquiry into an Amazonian Plant Brew
Crisis Intervention Related to the Use of Psychoactive Substances in Recreational Settings – Evaluating the Kosmicare Project at Boom Festival
Psychedelics as Medicines for Substance Abuse Rehabilitation: Evaluating Treatments with LSD, Peyote, Ibogaine and Ayahuasca
A Qualitative Report on the Subjective Experience of Intravenous Psilocybin Administered in an fMRI Environment
Salvinorin A and Related Compounds as Therapeutic Drugs for Psychostimulant-Related Disorders

Editorial (Thematic Issue: Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’)

Editorial

Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’

We are witnessing a revival of psychedelic research. An increasing number of studies investigating the therapeutic use of psychedelics are currently underway at some of the most renowned universities. Dedicating a second issue of ‘Current Drug Abuse Reviews’ to psychedelics aims to keep up with this blossoming field. With the availability of modern scientific instruments, psychedelic research is once again gaining a firm foothold in academia.

The idea of this special issue originated at the Interdisciplinary Conference on Psychedelic Research, organised by the OPEN Foundation in 2012. OPEN was founded in 2007 in the Netherlands, in order to stimulate and advance scientific research into psychedelics. This special issue of CDAR takes an interdisciplinary approach to the topic of psychedelics and mental health, while maintaining a particular focus on applications of psychedelics in the fields of substance abuse and addiction. This special issue also takes a critical look at some widespread assumptions about psychedelics, introduces new ideas and suggests novel directions for future research.

Kortekaas, R., & Breeksema, J. J. (2015). Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’. Current Drug Abuse Reviews, 7(2), 69-70. https://dx.doi.org/10.2174/1874473708666150120114604

Link to full text

Articles in this special issue:

Editorial (Thematic Issue: Introduction to ‘Beneficial Effects of Psychedelics with a Special Focus on Addictions’)
Ayahuasca, Psychedelic Studies and Health Sciences: The Politics of Knowledge and Inquiry into an Amazonian Plant Brew
Crisis Intervention Related to the Use of Psychoactive Substances in Recreational Settings – Evaluating the Kosmicare Project at Boom Festival
Psychedelics as Medicines for Substance Abuse Rehabilitation: Evaluating Treatments with LSD, Peyote, Ibogaine and Ayahuasca
A Qualitative Report on the Subjective Experience of Intravenous Psilocybin Administered in an fMRI Environment
Salvinorin A and Related Compounds as Therapeutic Drugs for Psychostimulant-Related Disorders

Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans

Abstract

Psychedelic agents have a long history of use by humans for their capacity to induce profound modifications in perception, emotion and cognitive processes. Despite increasing knowledge of the neural mechanisms involved in the acute effects of these drugs, the impact of sustained psychedelic use on the human brain remains largely unknown. Molecular pharmacology studies have shown that psychedelic 5-hydroxytryptamine (5HT)2A agonists stimulate neurotrophic and transcription factors associated with synaptic plasticity. These data suggest that psychedelics could potentially induce structural changes in brain tissue. Here we looked for differences in cortical thickness (CT) in regular users of psychedelics. We obtained magnetic resonance imaging (MRI) images of the brains of 22 regular users of ayahuasca (a preparation whose active principle is the psychedelic 5HT2A agonist N,N-dimethyltryptamine (DMT)) and 22 controls matched for age, sex, years of education, verbal IQ and fluid IQ. Ayahuasca users showed significant CT differences in midline structures of the brain, with thinning in the posterior cingulate cortex (PCC), a key node of the default mode network. CT values in the PCC were inversely correlated with the intensity and duration of prior use of ayahuasca and with scores on self-transcendence, a personality trait measuring religiousness, transpersonal feelings and spirituality. Although direct causation cannot be established, these data suggest that regular use of psychedelic drugs could potentially lead to structural changes in brain areas supporting attentional processes, self-referential thought, and internal mentation. These changes could underlie the previously reported personality changes in long-term users and highlight the involvement of the PCC in the effects of psychedelics.

Bouso, J. C., Palhano-Fontes, F., Rodríguez-Fornells, A., Ribeiro, S., Sanches, R., Crippa, J. A. S., … & Riba, J. (2015). Long-term use of psychedelic drugs Is associated with differences in brain structure and personality in humans. European Neuropsychopharmacology. http://dx.doi.org/10.1016/j.euroneuro.2015.01.008
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LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects

Abstract

Objective: A recently published study showed the safety and efficacy of LSD-assisted psychotherapy in patients with anxiety associated with life-threatening diseases. Participants of this study were included in a prospective follow-up.

Method: 12 months after finishing LSD psychotherapy, 10 participants were tested for anxiety (STAI) and participated in a semi-structured interview. A Qualitative Content Analysis (QCA) was carried out on the interviews to elaborate about LSD effects and lasting psychological changes.

Results: None of the participants reported lasting adverse reactions. The significant benefits as measured with the STAI were sustained over a 12-month period. In the QCA participants consistently reported insightful, cathartic and interpersonal experiences, accompanied by a reduction in anxiety (77.8%) and a rise in quality of life (66.7%). Evaluations of subjective experiences suggest facilitated access to emotions, confrontation of previously unknown anxieties, worries, resources and intense emotional peak experiences à la Maslow as major psychological working mechanisms. The experiences created led to a restructuring of the person’s emotional trust, situational understanding, habits and world view.

Conclusions: LSD administered in a medically supervised psychotherapeutic setting can be safe and generate lasting benefits in patients with a life-threatening disease. Explanatory models for the therapeutic effects of LSD warrant further study.

Gasser, P., Kirchner, K., & Passie, T. (2014). LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects. Journal of Psychopharmacology. https://dx.doi.org/10.1177/0269881114555249
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The potential religious relevance of entheogens

At least since William James, scholars of religion have wondered if mystical experiences induced by means of chemical substances are similar or identical to, and have the same value as, naturally occurring ones. Lengthy debates ensued throughout the 20th century, fuelled in part by scientific research such as the classic Good Friday experiment conducted in 1962 by Walter Pahnke. As the discussion on these experiences induced by external means, and their implications, goes on today, Zygon: Journal of Religion and Science (vol. 49, no. 3) has devoted a section of its September 2014 issue to the potential religious relevance of entheogens [fusion_builder_container hundred_percent=”yes” overflow=”visible”][fusion_builder_row][fusion_builder_column type=”1_1″ background_position=”left top” background_color=”” border_size=”” border_color=”” border_style=”solid” spacing=”yes” background_image=”” background_repeat=”no-repeat” padding=”” margin_top=”0px” margin_bottom=”0px” class=”” id=”” animation_type=”” animation_speed=”0.3″ animation_direction=”left” hide_on_mobile=”no” center_content=”no” min_height=”none”][1].

In the first of four articles, Ron Cole-Turner focuses on the recent psilocybin research at the neuropsychopharmacology group at Imperial College London by Carhart-Harris et al. (2014), whose findings depart from the view that psychedelics increase neural activity in the brain. On the contrary, the researchers found that psilocybin decreases neural activity in the default mode network [2], which they suggest is the “seat of the ego”. This result is “highly suggestive in terms of how psilocybin might function in the brain to “occasion” mystical experience,” Cole-Turner writes. The author however takes issue with the “pejorative” label of “magical thinking” the London researchers associate with the subjects’ supernatural interpretations of their experiences. Here, he draws a line between the London research team and the team at Johns Hopkins [3] that also studies psilocybin. For the former, mystical quality seems to be an unwanted side-effect, writes the author, while for the latter it is the very focus of research, and a desirable feature. “More than science is at play here, and more than religion is at stake”, Cole-Turner concludes, wondering what we will make of what we are about to discover.

In the second article, William Richards, who worked with Walter Pahnke in the 1960s and has himself worked on recent psilocybin research, starts by stating that psychedelics “provide two new factors critical for religious scholarship […], namely potency and reliability”. This means that meaningful experiences can be safely induced in most subjects, and the author notes that over 200 persons have now safely received psilocybin within the framework of the Johns Hopkins psilocybin research. He goes on to define mystical experiences and distinguishes them along three binary dimensions: complete and incomplete, unitive and personal, and internal and external mystical experience. His research [4] has shown that both aspects of these dimensions are not mutually exclusive, as some scholars of religion have argued, and can be experienced by the same person. Richards lays out two avenues of potential interdisciplinary research for scholars of religion: the study of religious groups that use entheogens in a sacramental way, and collaborations with colleagues from other fields in the design of interdisciplinary studies with entheogens.

The Santo Daime religious movement, which uses the Amazonian brew ayahuasca as its main sacrament, is the focus of the third article, written by G. William Barnard. In the first, introductory part, the author distinguishes between the productive and transmissive theories of the brain. In the latter, consciousness pre-exists the brain, which serves as a transmitter to the human body and mind. The productive theory, on the other hand, posits that consciousness is altogether produced by the brain. If we were to take the transmissive perspective, then mystical or religious experiences are not just “the hallucinatory byproducts of cerebral malfunctions caused by the chemical activity of these substances”, the author writes. In the second part of the article, Barnard goes on to sketch the history and main theological tenets of Santo Daime. He suggests that “[Huston] Smith’s [5] desire to see the birth of a modern day mystery school that revolves around the sacramental use of entheogens has, in fact, been fulfilled”, citing the Native American Church, and the Brazilian União do Vegetal religious group as other examples. In Barnard’s view, one of the primary reasons for Santo Daime church members to uphold their strict discipline is the extent of spiritual transformation and physical healing their practice provides.

In the last article, Leonard Hummel underscores the importance of lasting effects from mystical experiences, and notes that the Johns Hopkins study [6] did look for and found desirable long-term effects in the lives of participants. Hummel contends that the validity of drug-induced mystical experience is hardly ever questioned anymore, despite criticism that research focuses on the individual religious experience (“a momentary sense of wow”) rather than on its repercussions in the community. In his view, these criticisms are not in line with the reality of either ongoing (clinical) trials (which include questionnaires about the effects on the community practices of participants), or of existing religious communities such as Santo Daime or peyote churches. He also hypothesizes that the Council on Spiritual Practices intends to give rise to recognized entheogen-based religious communities in the US. Hummel does not envision, however, the use of entheogens in Christian communities in the US, underscoring – among other things – possible health hazards, due to the possible lack of an adequate setting. Therefore the author concludes that the administration of entheogens had better remain confined to a therapeutic setting.

All articles appear in the September edition of Zygon: Journal of Religion and Science (volume 49, no. 3), The Potential Religious Relevance of Entheogens.


 
[1] “Entheogen” is a synonym for “psychedelic” that is often used in a religious context. Literally, it means a compound that “generates the divine within”.
[2] The default mode network is a network of brain areas that is mainly active in a state of rest, when attention is more focused inwards than outwards.
[3] See for example Griffiths et al. (2006).
[4] Richards (2008).
[5] Huston Cummings Smith is a well-known religious studies scholar from the United States.
[6] Griffiths et al. (2006).
 
References
Barnard, G. William (2014). Entheogens in a Religious Context: The Case of the Santo Daime Religious Tradition. Zygon: Journal of Religion and Science, 49(3), 666-684. [Abstract]
Carhart-Harris, Robin L., Robert Leech, Peter J. Hellyer, Murray Shanahan, Amanda Feilding, Enzo Tagliazucchi, Dante R. Chialvo, and David J. Nutt (2014). The Entropic Brain: A Theory of Conscious States Informed by Neuroimaging Research with Psychedelic Drugs. Frontiers in Human Neuroscience 8. doi : 10.3389/fnhum.2014.00020 [Abstract]
Cole-Turner, Ron (2014). Entheogens, Mysticism, and Neuroscience. Zygon: Journal of Religion and Science, 49(3), 642-651. [Abstract]
Griffiths, R. R., Richards, W. A., McCann, U. & Jesse, R. (2006). Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance, Psychopharmacology, 187, 268–283. [Abtract]
Hummel, Leonard. By Its Fruits? Mystical and Visionary States of Consciousness Occasioned by Entheogens. Zygon: Journal of Religion and Science, 49(3), 685-695. [Abstract]
Richards, W. A. (2008). The Phenomenology and Potential Religious Import of States of Consciousness Facilitated by Psilocybin. Archive for the Psychology of Religion, 30, 189-199. [Abstract]
Richards William A. (2014). Here and Now: Discovering the Sacred with Entheogens. Zygon: Journal of Religion and Science, 49(3), 652-665. [Abstract][/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]

Ayahuasca Shamanism in the Amazon and Beyond

Ayahuasca Shamanism in the Amazon and Beyond, edited by Beatriz Caiuby Labate & Clancy Cavnar, Oxford University Press, 2014.

The editors presented this book recently at the 2014 World Ayahuasca Conference. This volume, part of the Oxford Ritual Studies series, provides us with the results of fieldwork done by a variety of anthropologists in many areas of the Amazon (Peru, Brazil and Colombia) and some areas outside of this region (Southern Brazil and urban centres in the region). It springs forth from the Amazon Conference: Amazonian Shamanism, Psychoactive Plants and Ritual Reinvention that took place at Heidelberg University in 2010.

The essays focus on different groups of people that use ayahuasca: on tribes that use ayahuasca in what is often considered a traditional setting, on tribes that have relatively recently adopted the use of ayahuasca, on mestizo shamanism and on the tourists that flow in mostly from North America and Europe. This diversity gives us a varied collection of essays, although all show how ayahuasca is used as a way to build culture and identity, as well as build connections between tribes and/or groups.

The picture that emerges out of the various essays is one that shows that some of the widespread ideas surrounding the history of ayahuasca as well as the way ayahuasca has been used traditionally are unfounded and in dire need of revision. It is shown for example that most tribes described in this volume only started using ayahuasca as we know it today relatively recently: some, like the Shipibo, around 150-200 years ago and others only since a few decades. This poses questions about ‘traditionality’ and how the use of ayahuasca has changed the cultural identity of these tribes. In general the authors conclude that the adoption of ayahuasca has caused such tribes to form their identity around the use of ayahuasca, while the growth of tourism has amplified this effect. Another effect of tourism is that the ‘traditional way to use ayahuasca’ has transformed through the expectations and conceptual frameworks of the tourists, which results in retreat centers that focus on personal development and healing with an eclectic approach that differs strongly from the ritual shamanic context within which the local population uses ayahuasca. Elements from other spiritual traditions are incorporated in the treatment, such as sweat lodges, Ayurvedic treatments, and so on. The essays show that these practices are shaped by cultural exchange, instead of a one-way dissemination of native wisdom.

The question whether this is a positive or negative development is only hinted at, but the message of the book is that, while it shows that the spread of ayahuasca is more recent than thought and that its use has furthermore transformed continuously throughout this process, the use of ayahuasca in the forming of cultural identities is no less legitimate. Summarily, the essays open up some new paths for researching the interplay between tradition, culture, identity and ayahuasca. This book is a welcome addition for those interested in the use of ayahuasca in the Amazon and beyond, for both anthropologists and those with an interest in ayahuasca in general. Highly recommended.

Buy this book through bookdepository.com and support the OPEN Foundation

By its fruits? Mystical and visionary states of consciousness occasioned by entheogens

Abstract

A new era has emerged in research on entheogens largely due to clinical trials conducted at Johns Hopkins University and similar studies sponsored by the Council for Spiritual Practices. In these notes and queries, I reflect on implications of these developments for psychological studies of religion and on what this research may mean for Christian churches in the United States. I conclude that the aims and methods of this research fit well within Jamesian efforts of contemporary psychology of religion to assess religious practices by their fruits for life. Furthermore, some communitarian religious concerns that religious experiences occasioned by entheogens pose risks to the integrity of religious community are shown to be largely unfounded. However, it is suggested that certain risks for religious life posed by all investigations/interventions by knowledge experts—in particular, the colonization of the religious life world and the commodification of its practices—also attend these developments for Christian churches. Additionally, risks of individual harm in the use of entheogens appear to be significant and, therefore, warrant earnest ethical study.

Hummel, L. (2014). By its fruits? Mystical and visionary states of consciousness occasioned by entheogens. Zygon: Journal of Religion and Science, 49(3), 685-695. http://dx.doi.org/10.1111/zygo.12112
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Entheogens in a religious context: The case of the Santo Daime religious tradition

Abstract

This essay first draws upon the work of William James and others to propose a nonphysicalistic understanding of the relationship between the brain and consciousness in order to articulate a philosophical perspective that can understand entheogenic visionary/mystical experiences as something other than hallucinations. It then focuses on the Santo Daime tradition, a religious movement that began in Brazil in the early part of the twentieth century, to provide an example of the personal and social ramifications of taking an entheogen (ayahuasca) within a disciplined religious context. The essay claims that the Santo Daime is one example of a contemporary mystery school; gives a brief history of the development of this religion; discusses the key theological assumptions of this movement; investigates the important role played by visionary/mystical experiences within this religion; underscores the centrality of healing and spiritual transformation for members of this tradition; and ends with an examination of the crucial significance of spiritual discipline within this entheogenically based religion.

Barnard, G. W. (2014). Entheogens in a religious context: The case of the Santo Daime religious tradition. Zygon: Journal of Religion and Science, 49(3), 666-684. http://dx.doi.org/10.1111/zygo.12109
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Here and now: Discovering the sacred with entheogens

Abstract

Renewed research with entheogens (psychedelic substances) has been able to facilitate the occurrence of mystical forms of consciousness in healthy volunteers with a high degree of reliability. This article explores the potential significance of this development for religious scholars, especially those interested in the study of mysticism. The definition of “mystical consciousness” employed in this research is presented and differentiated from visionary/archetypal and other types of alternative mental states. The ways in which entheogens may be employed with skill and maximum safety are discussed. Implications for clarifying confusion in the study of mysticism are considered, along with suggestions for future religious research on this frontier of knowledge.

Richards, W.  A. (2014). Here and now: Discovering the sacred with entheogens. Zygon: Journal of Religion and Science, 49(3), 652-665. http://dx.doi.org/10.1111/zygo.12108
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30 April - Q&A with Rick Strassman

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